Endocrine Abstracts

Osteoporosis may be a disease of unknown etiology, or a degenerative disorder in the context of aging. Nowadays, the availability of multiple forms of effective drug treatment for osteoporosis have raised the hypothesis that osteoporosis may be not only a treatable but moreover a curable disease.The aim was to describe the case of a patient with osteoporosis who after treatment with alendronate for 6 years had osteopenia and remains in the state of osteo...

Primary hyperparathyroidism is known to coexist with thyroid cancer and breast cancer. However, primary hyperparathyroidism coexisting with Graves’ disease is extremely rare. The aim was to describe the case of a patient with Graves’ disease causing severe hyperthyroidism who in the course of the disease developed vitamin D deficiency and primary hyperparathyroidism. A patient, female, aged 49 years, presented with severe hyperthyroidism causing tachycardia, palpitat...

Osteoporosis is a bone disease predisposing to bone fragility. Nowadays, the population is screened for osteoporosis and measures are taken for fracture prevention. Additionally, people are urged to have a diet rich in calcium, are given calcium supplements and are being treated for vitamin D deficiency. Moreover, osteoporosis treatment is administered. Therefore, the relationship between osteoporosis and fractures in the real world setting is very interesting.<p class="ab...

Primary hyperparathyroidism is a disease which nowadays is being diagnosed with increasing frequency. The diagnosis of primary hyperparathyroidism is based on routine calcium measurement, which if detected abnormally elevated leads to the screening of the patient for primary hyperparathyroidism. Therefore, primary hyperparathyroidism is frequently detected early in the course of the disease. Consequently, severe musculoskeletal manifestations may be lacking in the modern world...

Thyroid cancer is the most frequent endocrine cancer. Its incidence has been found to increase in recent years. Additionally, environmental factors, which may be implicated in the pathogenesis of thyroid disorders, such as iodine deficiency and salt iodine supplementation are changing and may have an impact on the epidemiology of thyroid cancer. The aim was to study the epidemiology of thyroid within a center of excellence in Athens in the modern world setting. A cohort of 63 ...

Introduction: Osteoporosis is a chronic and dangerous disease, as it may be silent and may express itself with a sudden catastrophic event, such as a fracture. Treatment of osteoporosis demands the use of potent pharmaceutical agents with long lasting effects. In particular, bisphosphonates, such as ibandronate, may be used. It has become evident that chronic treatment with anti-osteoporotic agents may reverse the course of the disease, patients having normal bone mineral dens...

Introduction: Von Hippel-Lindau (VHL) syndrome is an inherited disorder characterized by the formation of tumors and cysts in diverse organ systems. Tumors may be malignant or benign and they tend to appear during young adulthood. Hemangioblastomas are characteristic of VHL syndrome.Aim: The aim was to describe the case of a patient with VHL syndrome presenting with musculoskeletal manifestations and multiple tumors.Case report: A ...

Introduction: Vitamin D deficiency has been reported to be widely found within the population. Vitamin D deficiency was also found to be prevalent in patients with autoimmune inflammatory diseases such as rheumatoid arthritis and systemic lupus erythematosus. Vitamin D deficiency was reported in almost all patients with acute myocardial infarction in a US multicenter study. Low concentrations of 25-hydroxyvitamin D (25(OH)D) are reported to be an independent risk factor for ca...

Introduction: Primary hyperparathyroidism is currently a frequent disorder. In the past primary hyperparathyroidism was diagnosed late in the course of the disease. With the introduction of routine calcium measurements, as well as the awareness of the disease amongst clinicians, the disorder is frequently recognized in asymptomatic patients. Thus, the clinical profile of primary hyperparathyroidism is changing.Aim: The aim was to describe the clinical pr...

Introduction: Graves’ disease is a multi-system autoimmune disease characterized by hyperthyroidism, ophthalmopathy and pretibial myxedema. The disease presents with hyperthyroidism or more rarely with ophthalmopathy. It runs a various course and many times during its natural course permanent hypothyroidism may ensue.Aim: The aim was to describe the case of a patient with Graves’ disease presenting with ophthalmopathy and subclinical hypothyroi...